Description: The MLL1 Complex Direct Activity Chemiluminescent Assay kit is designed to measure_x000D_MLL1 activity for screening and profiling applications, using purified MLL1 and its_x000D_complex components: WDR5, RbBP5,Ash2, and DPY30. The key to the MLL1_x000D_Complex Chemiluminescent Assay Kit is a highly specific antibody that recognizes_x000D_methylated K4 residue of Histone H3. With this kit, only three simple steps on a_x000D_microtiter plate are required for methyltransferase detection. First, S-adenosylmethionine_x000D_is incubated with a sample containing assay buffer and methyltransferase enzyme for one_x000D_hour. Next, primary antibody is added. Finally, the plates are treated with an HRP-labeled_x000D_secondary antibody followed by the addition of the HRP substrate to produce_x000D_chemiluminescence that can be measured using a chemiluminescence reader.

Description: The MLL4 Complex Chemiluminescent Assay Kit is designed to measure MLL4 activity for screening and profiling applications, using purified MLL4 and its complex components: WDR5, RbBP5, Ash2, and DPY30. The key to the MLL4 Complex Chemiluminescent Assay Kit is a highly specific antibody that recognizes methylated K4 residue of Histone H3. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, S-adenosylmethionine is incubated with a sample containing assay buffer and methyltransferase enzyme. Next, primary antibody is added. Finally, the plates are treated with an HRP-labeled secondary antibody followed by the addition of the HRP substrate to produce chemiluminescence that can be measured using a chemiluminescence reader.

Description: The MLL3 Complex Chemiluminescent Assay Kit is designed to measure MLL3 activity for screening and profiling applications, using purified MLL3 and its complex components: WDR5, RbBP5, Ash2, and DPY30. The key to the MLL3 Complex Chemiluminescent Assay Kit is a highly specific antibody that recognizes methylated K4 residue of Histone H3. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, S-adenosylmethionine is incubated with a sample containing assay buffer and methyltransferase enzyme. Next, primary antibody is added. Finally, the plates are treated with an HRP-labeled secondary antibody followed by the addition of the HRP substrate to produce chemiluminescence that can be measured using a chemiluminescence reader.

Description: Traditionally, the soft agar colony formation assay has been used to monitor anchorage-independent growth. Cells proliferate for 3-4 weeks in a semisolid culture medium, followed by tedious manual counting of colonies. Our CytoSelect 96-Well In Vitro Tumor Sensitivity Assay provides a stringent, anchorage-independent model for chemosenstivity testing and screening of potential anticancer drugs. After just 6-8 days, cell colonies are quantified using a standard colorimetric microplate reader.

Description: Enzyme Activity

Description: Enzyme Activity

Description: Enzyme Activity