Principle Of Comeptitive Binding Assay

Cereblon Binding Assay Kit
79899 BPS Bioscience 96 rxns. 600 EUR
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader.

Binding Assay Laboratories manufactures the principle of comeptitive binding assay reagents distributed by Genprice. The Principle Of Comeptitive Binding Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact binding assay. Other Principle products are available in stock. Specificity: Principle Category: Of Group: Comeptitive Binding

XTT CELL VIABILITY ASSAY KIT (1000 ASSAY)
Biotium 1KIT 283.2 EUR
Description: Minimum order quantity: 1 unit of 1KIT

IDO1 Inhibitor Mechanism of Action Assay Kit
BPS Bioscience 50 rxns. 745 EUR
Description: The IDO1 Inhibitor Mechanism of Action (MoA) Assay Kit is designed to_x000D_determine the mechanism of IDO1 enzyme inhibition (e.g., reversible or irreversible inhibition)._x000D_The IDO1 Mechanism of Action Assay Kit is simple to use. Inhibitor and_x000D_enzyme are preincubated allowing the inhibitor to bind. After preincubation, the mixture is_x000D_diluted into reaction buffer containing the L-tryptophan (L-Trp) substrate and all necessary_x000D_coupled reaction components. This allows reversible inhibitors to dissociate, while irreversible_x000D_inhibitors remain associated with the IDO1 enzyme. IDO1 activity is determined by measuring_x000D_the absorption of the reaction product at =320 - 325 nm.

Total Iron-Binding Capacity (TIBC) and Serum Iron Assay Kit (Colorimetric)
Biovision each 698.4 EUR

MTT Cell Proliferation and Cytotoxicity Assay Kit
BosterBio 1 kit (for 500 assays) 115.2 EUR

CF488A and 7-AAD Apoptosis Assay Kit
Biotium 1KIT 339.6 EUR
Description: Minimum order quantity: 1 unit of 1KIT

MTT Cell Proliferation and Cytotoxicity Assay Kit
Abbexa 500 tests 284.4 EUR

Cell Proliferation and Cytotoxicity MTT Assay Kit
GenDepot 100 Assays 198 EUR

Comeptitive Binding information

EpiQuik BRD2 Binding Activity/Inhibition Assay Kit (Colorimetric)
P-4058 EpiGentek 96 Assays 1032.66 EUR

Cell Meterâ„¢ Live Cell Caspase 1 Binding Assay Kit *Green Fluorescence*
20108-25Tests AAT Bioquest 25 Tests 334 EUR
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 2 Binding Assay Kit *Green Fluorescence*
20111-25Tests AAT Bioquest 25 Tests 334 EUR
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 6 Binding Assay Kit *Green Fluorescence*
20113-25Tests AAT Bioquest 25 Tests 334 EUR
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 8 Binding Assay Kit *Green Fluorescence*
20115-25Tests AAT Bioquest 25 Tests 334 EUR
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 9 Binding Assay Kit *Green Fluorescence*
20117-25Tests AAT Bioquest 25 Tests 334 EUR
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 10 Binding Assay Kit *Green Fluorescence*
20119-25Tests AAT Bioquest 25 Tests 334 EUR
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence*
20125-25Tests AAT Bioquest 25 Tests 334 EUR
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meter™ Live Cell Caspase 8 Binding Assay Kit *Red Fluorescence*
20116 AAT Bioquest 25 Tests 372 EUR

Cell Meterâ„¢ Live Cell Caspase 3/7 Binding Assay Kit *Red Fluorescence*
20101-25Tests AAT Bioquest 25 Tests 334 EUR
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meter™ Live Cell Caspase 1 Binding Assay Kit *Green Fluorescence*
20108 AAT Bioquest 25 Tests 334 EUR

Cell Meter™ Live Cell Caspase 2 Binding Assay Kit *Green Fluorescence*
20111 AAT Bioquest 25 Tests 334 EUR

Cell Meter™ Live Cell Caspase 6 Binding Assay Kit *Green Fluorescence*
20113 AAT Bioquest 25 Tests 334 EUR

Cell Meter™ Live Cell Caspase 8 Binding Assay Kit *Green Fluorescence*
20115 AAT Bioquest 25 Tests 334 EUR

Cell Meter™ Live Cell Caspase 9 Binding Assay Kit *Green Fluorescence*
20117 AAT Bioquest 25 Tests 334 EUR

Cell Meter™ Live Cell Caspase 10 Binding Assay Kit *Green Fluorescence*
20119 AAT Bioquest 25 Tests 334 EUR

Cell Meter™ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence*
20125 AAT Bioquest 25 Tests 334 EUR